Shanghai Orsin Medical Technology Co., Ltd.
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The EDTA K2 blood collection tube, containing dipotassium ethylenediaminetetraacetic acid (EDTA-K₂) as an anticoagulant, functions by chelating calcium ions in blood to inhibit the coagulation cascade, thereby preserving the original morphology of blood cells ex vivo. Its clinical roles and significance include:
Gold Standard for Hematology Testing: As the preferred anticoagulant for complete blood count (CBC) and blood smear examinations, it ensures accuracy in white blood cell differentials, red cell morphology, and platelet counts;
Cellular Stability Maintenance: EDTA-K₂ prevents platelet aggregation and minimizes cell lysis, making it critical for assays requiring intact cells (e.g., flow cytometry for CD4/CD8 counts);
Standardized Laboratory Practice: Recommended by the International Council for Standardization in Haematology (ICSH) for routine hematology testing, ensuring result comparability and reliability;
Diagnostic Value: Provides essential data for screening, diagnosing, and monitoring conditions such as anemia, infections, hematologic malignancies (e.g., leukemia), and thrombotic disorders.
Note: Gently invert the tube 8-10 times post-collection; samples should be analyzed within 4 hours to prevent cellular degradation affecting results.